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Structure of 403-01-0
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Methyl 3-fluoro-4-hydroxybenzoate features a strategically positioned fluorine atom and hydroxyl group on the aromatic ring, enabling precise electronic tuning and enhanced solubility. This ortho-directing functionality facilitates efficient downstream derivatization in synthetic organic chemistry and pharmaceutical intermediates.
Methyl 3-fluoro-4-hydroxybenzoate serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the phenolic hydroxyl group while maintaining compatibility with standard coupling and derivatization protocols. The ortho-fluoro substituent facilitates nucleophilic aromatic substitution under mild conditions, enhancing synthetic versatility for heterocyclic and API scaffold construction. Bench-stable and readily purified by recrystallization, it functions efficiently in multi-step syntheses requiring orthogonal reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: