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Structure of 35112-05-1
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4-Chloro-2-fluoro-5-nitrobenzoic acid features a trifunctional aromatic core with orthogonal reactivity. The carboxylic acid group enables direct coupling or derivatization, while the electron-deficient ring facilitates nucleophilic substitution. This scaffold offers enhanced stability and predictable regioselectivity in synthetic transformations.
4-Chloro-2-fluoro-5-nitrobenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the carboxylic acid and nitro groups. Its electron-withdrawing fluorine and chlorine substituents enhance reactivity in nucleophilic aromatic substitution and facilitate downstream coupling reactions. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for use in multi-step syntheses of complex heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: