6-Chloro-4-iodopyridin-3-amine

Name: 6-Chloro-4-iodopyridin-3-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 351227-42-4
Cat. No. CS-0041406
Purity≥98%
MDL No.MFCD11520341

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Chloro-4-iodopyridin-3-amine|CS-0041406

Structure of 351227-42-4

Size

Price

Quantity

* Please select Quantity before adding items.

Description

6-Chloro-4-iodopyridin-3-amine features a pyridine core functionalized with chlorine and iodine at the 6- and 4-positions, respectively, enabling efficient cross-coupling transformations. The amino group at C3 provides a reactive handle for derivatization, while the electron-withdrawing halogens enhance electrophilicity for palladium-catalyzed reactions. This scaffold demonstrates robust stability under standard conditions and is well-suited for constructing complex heterocyclic architectures in medicinal chemistry and materials science applications.

Application

6-Chloro-4-iodopyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The iodine group facilitates efficient Suzuki, Stille, and Negishi couplings, while the chloro substituent offers orthogonal reactivity for sequential functionalization. Its amine functionality enables direct derivatization or incorporation into heterocyclic scaffolds. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis workflows in API development.

General Information

CAS No. 351227-42-4
Cat. No. CS-0041406
Purity ≥98%
MDL No. MFCD11520341
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₄ClIN₂
Molecular Weight 254.46
Synonym(s) 3-Pyridinamine, 6-chloro-4-iodo-
SMILES NC1=CN=C(Cl)C=C1I

Computational Chemistry Data

TPSA 38.91
LogP 1.9218
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Iodide

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

6-Chloro-4-iodopyridin-3-amine sigma6-Chloro-4-iodopyridin-3-amine manufacturer6-Chloro-4-iodopyridin-3-amine price6-Chloro-4-iodopyridin-3-amine structure6-Chloro-4-iodopyridin-3-amine SDSbuy 6-Chloro-4-iodopyridin-3-amine6-Chloro-4-iodopyridin-3-amine supplier6-Chloro-4-iodopyridin-3-amine uses6-Chloro-4-iodopyridin-3-amine molecular weightprice of 6-Chloro-4-iodopyridin-3-amine6-Chloro-4-iodopyridin-3-amine chemical name formula of 6-Chloro-4-iodopyridin-3-amine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Chloro-4-iodopyridin-3-amine

CAS No. 351227-42-4

Recommended Products