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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,4-dichlorophenyl)propanoic acid

  • CAS No. 352351-62-3

  • Cat. No. CS-0097852
  • Molecule weight456.32
  • Purity≥97%
  • MDL No.MFCD01863048

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,4-dichlorophenyl)propanoic acid|CS-0097852

Structure of 352351-62-3

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General Information

  • CAS No. 352351-62-3
  • Cat. No. CS-0097852
  • Purity ≥97%
  • MDL No. MFCD01863048
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₁₉Cl₂NO₄
  • Molecular Weight 456.32
  • Synonym(s) L-phenylalanine, 2,4-dichloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
  • SMILES O=C(O)[C@H](CC1=CC=C(Cl)C=C1Cl)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,4-dichlorophenyl)propanoic acid serves as a key chiral building block for the synthesis of peptidomimetic scaffolds and bioactive heterocycles. The fluorenylmethoxycarbonyl (Fmoc) group enables orthogonal protection during solid-phase peptide synthesis, while the 2,4-dichlorophenyl moiety provides enhanced metabolic stability and favorable lipophilicity. This compound exhibits excellent bench stability, facilitates straightforward purification via flash chromatography, and participates reliably in standard amide coupling protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   5.5278
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   6

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