Fmoc-L-β-Homo-Trp-OH

Name: Fmoc-L-β-Homo-Trp-OH
Brand: ChemScene
Availability: InStock
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CAS No. 353245-98-4
Cat. No. CS-0062195
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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*For research and further manufacturing use only, not for direct human use.

Structure of 353245-98-4

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Description

Fmoc-L-β-Homo-Trp-OH features a β-homologated tryptophan scaffold with an N-terminal Fmoc protecting group, enabling seamless incorporation into peptide chains. The indole side chain retains inherent electron-rich character, supporting π–π interactions and hydrophobic packing in folded structures. This derivative offers enhanced stability and solubility under standard coupling conditions, streamlining synthesis of bioactive peptides.

Application

Fmoc-L-β-Homo-Trp-OH serves as a valuable building block in peptide synthesis, enabling the incorporation of β-homotryptophan residues with enhanced conformational diversity. The Fmoc group provides orthogonal protection for the α-amino function, facilitating efficient coupling under standard solid-phase conditions. This derivative exhibits excellent bench stability, tolerates common reaction conditions, and supports facile purification via flash chromatography or crystallization, making it well-suited for both research-scale and process-oriented peptide assembly.

General Information

CAS No. 353245-98-4
Cat. No. CS-0062195
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₇H₂₄N₂O₄
Molecular Weight 440.49
Synonym(s) N-BETA-FMOC-L-BETA-HOMOTRYPTOPHAN
SMILES O=C(O)C[C@H](CC1=CNC2=CC=CC=C12)NC(OCC3C4=CC=CC=C4C5=CC=CC=C53)=O

Computational Chemistry Data

TPSA 91.42
LogP 5.0924
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 7

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Fmoc-L-β-Homo-Trp-OH

CAS No. 353245-98-4

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