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CS-W001157 4
Total: USD 88.00

Ethyl 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate

  • CAS No. 353258-31-8

  • Cat. No. CS-0035478
  • Molecule weightNone
  • Purity≥96%
  • MDL No.MFCD01833013

*For research and further manufacturing use only, not for direct human use.

Ethyl 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate|CS-0035478

Structure of 353258-31-8

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General Information

  • CAS No. 353258-31-8
  • Cat. No. CS-0035478
  • Purity ≥96%
  • MDL No. MFCD01833013
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈ClF₃N₂O₂
  • Molecular Weight None
  • Synonym(s) Imidazo[1,2-a]pyridine-2-carboxylic acid, 8-chloro-6-(trifluoromethyl)-, ethyl ester
  • SMILES CCOC(=O)C1=CN2C=C(C=C(C2=N1)Cl)C(F)(F)F

Synthesis

  • Route1
    • null|null
      70-23-5
    • In-stock
      3-Chloro-5-(trifluoromethyl)pyridin-2-amine|CS-W010581
      79456-26-1
    • ~93%
    • In-stock
      Ethyl 8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate|CS-0035478
      353258-31-8

    References

    • EXELIXIS, INC.; CANNE BANNEN, Lynne; CHAN, Diva Sze-ming; GU, Xiao-hui; MAC, Morrison, B.; NG, Stephanie; WANG, Tie-lin; WANG, Yong; XU, Wei Patent: WO2010/65760 A1, 2010 ; Location in patent: Page/Page column 102 ; WO 2010/065760 A1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.6
  • LogP   3.1832
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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