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CS-W001157 4
Total: USD 88.00

1,4-Bis(bromomethyl)cyclohexane

  • CAS No. 35541-75-4

  • Cat. No. CS-0320230
  • Molecule weight270.00
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,4-Bis(bromomethyl)cyclohexane|CS-0320230

Structure of 35541-75-4

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General Information

  • CAS No. 35541-75-4
  • Cat. No. CS-0320230
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₄Br₂
  • Molecular Weight 270.00
  • Synonym(s) 1,4-Bis-bromomethyl-cyclohexane
  • SMILES C1CC(CCC1CBr)CBr

Description

1,4-Bis(bromomethyl)cyclohexane features two bromomethyl groups positioned at opposite ends of a cyclohexane ring, enabling efficient bifunctional coupling in synthesis. This rigid, bench-stable scaffold facilitates the construction of cyclic architectures and macrocyclic systems under standard conditions.

Application

1,4-Bis(bromomethyl)cyclohexane serves as a versatile difunctional building block for the synthesis of cyclic and macrocyclic architectures. Its bromomethyl groups enable efficient nucleophilic substitution and transition-metal-catalyzed coupling reactions, facilitating the construction of complex scaffolds with controlled stereochemistry. The molecule exhibits good bench stability and is readily purified by distillation or chromatography, making it well-suited for scalable synthetic applications in medicinal chemistry and materials science.

Synthesis

  • Route1

    References

    • Golobish, Thomas D.; Dailey, William P. Journal of Organic Chemistry, 1995 , vol. 60, # 24 p. 7865 - 7869

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.5826
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

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