(S)-Benzyl (2-oxotetrahydrofuran-3-yl)carbamate

Name: (S)-Benzyl (2-oxotetrahydrofuran-3-yl)carbamate
Brand: ChemScene
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CAS No. 35677-89-5
Cat. No. CS-W012893
Purity≥98%
MDL No.MFCD00674555

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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(S)-Benzyl (2-oxotetrahydrofuran-3-yl)carbamate|CS-W012893

Structure of 35677-89-5

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Description

This chiral building block features a (S)-configured benzyl carbamate tethered to a 2-oxotetrahydrofuran-3-yl moiety, offering high stereocontrol in asymmetric synthesis. The oxo group enhances reactivity for downstream functionalization, while the carbamate handle enables selective protection and cleavage under mild conditions.

Application

(S)-Benzyl (2-oxotetrahydrofuran-3-yl)carbamate serves as a chiral building block for the synthesis of tetrahydrofuran-containing pharmaceuticals and natural products. Its functionality enables straightforward access to enantiopure heterocycles via reductive amination, nucleophilic addition, or ring-opening reactions. The carbamate group provides stability and facilitates purification, while the oxo substituent offers a handle for further functionalization. This compound is bench-stable and compatible with standard synthetic workflows.

General Information

CAS No. 35677-89-5
Cat. No. CS-W012893
Purity ≥98%
MDL No. MFCD00674555
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₃NO₄
Molecular Weight 235.24
Synonym(s) N-Z-L-homoserine lactone
SMILES O=C1[C@@H](NC(OCC2=CC=CC=C2)=O)CCO1

Computational Chemistry Data

TPSA 64.63
LogP 1.2283
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydrofuran compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

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(S)-Benzyl (2-oxotetrahydrofuran-3-yl)carbamate

CAS No. 35677-89-5

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