7-Chloro-1H-pyrrolo[3,2-b]pyridine

Name: 7-Chloro-1H-pyrrolo[3,2-b]pyridine
Brand: ChemScene
Availability: InStock
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CAS No. 357263-48-0
Cat. No. CS-W019635
Purity≥95%
MDL No.MFCD08234945

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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7-Chloro-1H-pyrrolo[3,2-b]pyridine|CS-W019635

Structure of 357263-48-0

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Description

7-Chloro-1H-pyrrolo[3,2-b]pyridine is a heterocyclic scaffold featuring a chlorinated pyrrolopyridine core with enhanced electron deficiency. This bench-stable, moisture-tolerant compound integrates readily into synthetic routes for pharmaceutical intermediates and functional materials. Its planar structure supports π–π interactions in crystal engineering applications.

Application

7-Chloro-1H-pyrrolo[3,2-b]pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to biologically relevant scaffolds. Its electron-deficient pyridine core facilitates transition metal-catalyzed couplings and nucleophilic substitution reactions. The chlorine substituent provides a reliable handle for further functionalization, while the fused ring system offers enhanced metabolic stability and predictable reactivity in standard synthetic workflows.

General Information

CAS No. 357263-48-0
Cat. No. CS-W019635
Purity ≥95%
MDL No. MFCD08234945
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅ClN₂
Molecular Weight None
Synonym(s) 1H-pyrrolo[3,2-b]pyridine, 7-chloro-
SMILES ClC1=C2C(C=CN2)=NC=C1

Computational Chemistry Data

TPSA 28.68
LogP 2.2163
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Key Words

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7-Chloro-1H-pyrrolo[3,2-b]pyridine

CAS No. 357263-48-0

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