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Structure of 358780-14-0
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1-(6-(Trifluoromethyl)pyridin-3-yl)ethanone features a trifluoromethyl group at the pyridine ring's 6-position, enhancing electron deficiency and metabolic stability. This ketone moiety integrates readily into synthetic routes for pharmaceutical intermediates, offering high reactivity in nucleophilic additions and compatibility with diverse functional groups under standard conditions.
1-(6-(Trifluoromethyl)pyridin-3-yl)ethanone serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds via nucleophilic substitution and coupling reactions. Its trifluoromethyl-pyridyl motif imparts enhanced metabolic stability and lipophilicity, while the acetyl group provides a handle for derivatization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: