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Structure of 3590-48-5
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5-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione features a reactive chloromethyl group flanked by two carbonyl functionalities, enabling selective alkylation under mild conditions. This electrophilic handle integrates readily into nucleophilic substrates, serving as a key intermediate in the synthesis of functionalized pyrimidine derivatives for medicinal chemistry applications.
5-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione serves as a versatile building block for the synthesis of pyrimidine-based heterocycles, enabling efficient functionalization at the C5 position. The chloromethyl group facilitates nucleophilic substitution reactions, supporting the construction of diverse scaffolds with high regioselectivity. Its bench-stable nature and compatibility with common reaction conditions make it well-suited for medicinal chemistry campaigns and process-scale derivatization.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314-H318
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: