N-(4-Ethylphenyl)acetamide

Name: N-(4-Ethylphenyl)acetamide
Brand: ChemScene
Availability: InStock
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CAS No. 3663-34-1
Cat. No. CS-0226195
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 3663-34-1

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Description

N-(4-Ethylphenyl)acetamide is a bench-stable aromatic amide featuring a para-ethyl-substituted phenyl ring linked via an acetamide tether. This configuration delivers enhanced solubility in organic solvents and facilitates integration into pharmaceutical intermediates and functional materials, where its electron-rich aryl group supports efficient coupling reactions under standard conditions.

Application

N-(4-Ethylphenyl)acetamide serves as a versatile intermediate in medicinal chemistry, enabling efficient construction of aromatic amide scaffolds. Its ethyl-substituted phenyl ring enhances lipophilicity and metabolic stability, while the acetamide group provides a robust handle for further functionalization via hydrolysis, reduction, or coupling reactions. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows for API development and heterocyclic core assembly.

General Information

CAS No. 3663-34-1
Cat. No. CS-0226195
Purity ≥97%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₃NO
Molecular Weight 163.22
Synonym(s) p-Ethylacetanilide
SMILES CC(NC1=CC=C(CC)C=C1)=O

Computational Chemistry Data

TPSA 29.1
LogP 2.2074
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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N-(4-Ethylphenyl)acetamide

CAS No. 3663-34-1

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