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*For research and further manufacturing use only, not for direct human use.
Structure of 367-12-4
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2-Fluorophenol delivers a reactive ortho-fluorinated aromatic scaffold ideal for pharmaceutical and agrochemical synthesis. The fluorine substituent enhances metabolic stability and modulates electronic properties, while the phenolic hydroxyl enables direct functionalization or hydrogen bonding in target molecules. This bench-stable compound integrates readily into complex molecular architectures under standard conditions.
2-Fluorophenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the ortho position relative to the hydroxyl group. Its enhanced electrophilicity compared to phenol facilitates nucleophilic aromatic substitution and transition-metal-catalyzed coupling reactions. The molecule exhibits good bench stability and compatibility with common protecting group strategies, making it suitable for multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Warning
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H315-H319
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P280-P362+P364-P370+P378-P501
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Lot numbers can be found on the outside label of a product: