Lot numbers can be found on the outside label of a product:
1-(4-Bromo-3-methylphenyl)ethanone
-
CAS No. 37074-40-1
- Cat. No. CS-0153206
- Purity≥98%
- MDL No.MFCD00045017
*For research and further manufacturing use only, not for direct human use.
Structure of 37074-40-1
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 37074-40-1
- Cat. No. CS-0153206
- Purity ≥98%
- MDL No. MFCD00045017
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₉BrO
- Molecular Weight 213.07
- Synonym(s) Ethanone, 1-(4-broMo-3-Methylphenyl)-
- SMILES CC1=CC(=CC=C1Br)C(=O)C
Description
1-(4-Bromo-3-methylphenyl)ethanone features a brominated aromatic ring flanked by a methyl group and a ketone-bearing side chain, enabling direct integration into cross-coupling and functionalization workflows. The electron-deficient aryl moiety pairs effectively with palladium catalysts under standard conditions, while the bench-stable ketone offers a reliable handle for further derivatization in synthetic sequences.
Application
1-(4-Bromo-3-methylphenyl)ethanone serves as a versatile building block for the synthesis of biologically active molecules and pharmaceutical intermediates. Its structure features a brominated aromatic ring with a methyl group in close proximity to a ketone functionality, enabling selective functionalization via cross-coupling reactions. The ketone group provides a handle for further transformations such as reduction, nucleophilic addition, or enolization, while the aryl bromide supports palladium-catalyzed coupling processes. Bench-stable and readily purified by recrystallization or column chromatography, it integrates efficiently into multi-step synthetic sequences.
Synthesis
-
Route1
-
51930-77-9 - ~10%
-
In-stock
37074-40-1
References
-
CONSTELLATION PHARMACEUTICALS; ALBRECHT, Brian, K.; AUDIA, James, Edmund; COOK, Andrew; GAGNON, Alexandre; HARMANGE, Jean-christophe; NAVESCHUK, Christopher, G. Patent: WO2013/75083 A1, 2013 ; Location in patent: Paragraph 00492; 00494 ;
-
-
Route2
-
In-stock
43230-11-1 - ~86%
-
In-stock
37074-40-1
References
-
Nissan Chemical Industries, Ltd. Patent: EP2172462 A1, 2010 ; Location in patent: Page/Page column 73-74 ;
-
-
Route3
-
In-stock
7697-28-1 - ~%
-
In-stock
37074-40-1
References
-
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; KUHN, Cyrille; BHARDWAJ, Punit K .; POUPART, Marc-Andre Patent: WO2011/91532 A1, 2011 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 17.07
- LogP 2.96012
- H_Acceptors 1
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 1-(4-Bromo-3-methylphenyl)ethanone sigma1-(4-Bromo-3-methylphenyl)ethanone manufacturer1-(4-Bromo-3-methylphenyl)ethanone price1-(4-Bromo-3-methylphenyl)ethanone structure1-(4-Bromo-3-methylphenyl)ethanone SDSbuy 1-(4-Bromo-3-methylphenyl)ethanone1-(4-Bromo-3-methylphenyl)ethanone supplier1-(4-Bromo-3-methylphenyl)ethanone uses1-(4-Bromo-3-methylphenyl)ethanone molecular weightprice of 1-(4-Bromo-3-methylphenyl)ethanone1-(4-Bromo-3-methylphenyl)ethanone chemical name formula of 1-(4-Bromo-3-methylphenyl)ethanone