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Structure of 37098-75-2
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5-(Chlorosulfonyl)-2-fluorobenzoic acid features a strategically positioned chlorosulfonyl group flanked by a fluorine substituent and carboxylic acid functionality, enabling direct conjugation in synthetic transformations. This arrangement supports efficient derivatization under mild conditions, particularly valuable for probe design and bioconjugation workflows requiring selective reactivity.
5-(Chlorosulfonyl)-2-fluorobenzoic acid serves as a versatile bifunctional building block for the synthesis of sulfonamide-containing heterocycles and bioactive molecules. The chlorosulfonyl group enables efficient nucleophilic substitution with amines to form sulfonamides, while the carboxylic acid facilitates coupling reactions via standard amide bond formation. Its bench-stable nature and orthogonal reactivity profile make it ideal for multi-step synthetic sequences in medicinal chemistry and API development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P280-P301+P330+P331-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: