4'-Amino-3',5'-dichloroacetophenone

Name: 4'-Amino-3',5'-dichloroacetophenone
Brand: ChemScene
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CAS No. 37148-48-4
Cat. No. CS-W005483
Purity≥98%
MDL No.MFCD00238535

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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4'-Amino-3',5'-dichloroacetophenone|CS-W005483

Structure of 37148-48-4

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Application

4'-Amino-3',5'-dichloroacetophenone serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling the construction of substituted aromatic scaffolds via standard coupling reactions. The ortho-dichloro substitution pattern enhances regioselectivity in electrophilic transformations, while the amino and ketone functionalities offer complementary handles for derivatization. Bench-stable and compatible with common purification methods, it facilitates efficient access to complex heterocyclic systems and functionalized aryl motifs in multi-step syntheses.

General Information

CAS No. 37148-48-4
Cat. No. CS-W005483
Purity ≥98%
MDL No. MFCD00238535
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇Cl₂NO
Molecular Weight 204.05
Synonym(s) 4-Acetyl-2,6-dichloroaniline
SMILES C1=C(C=C(Cl)C(=C1Cl)N)C(C)=O

Computational Chemistry Data

TPSA 43.09
LogP 2.7782
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Ketone

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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4'-Amino-3',5'-dichloroacetophenone

CAS No. 37148-48-4

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