(1R,2S)-2-Phenylcyclopropan-1-amine

Name: (1R,2S)-2-Phenylcyclopropan-1-amine
Brand: ChemScene
Availability: InStock
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CAS No. 3721-26-4
Cat. No. CS-0099373
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(1R,2S)-2-Phenylcyclopropan-1-amine|CS-0099373

Structure of 3721-26-4

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Description

This chiral cyclopropanamine features a rigid, strained three-membered ring system with defined stereochemistry at the 1R,2S configuration. The phenyl group imparts aromatic character and steric influence, while the primary amine enables facile derivatization. Ideal for asymmetric synthesis and medicinal chemistry applications requiring conformational constraint and precise spatial orientation.

Application

(1R,2S)-2-Phenylcyclopropan-1-amine serves as a stereochemically defined building block for bioactive molecule synthesis, offering high functional group tolerance and bench stability. Its constrained cyclopropane scaffold enables precise spatial orientation in medicinal chemistry applications, facilitating efficient coupling reactions and serving as a key intermediate in the construction of heterocyclic frameworks relevant to CNS-targeted therapeutics.

General Information

CAS No. 3721-26-4
Cat. No. CS-0099373
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₁N
Molecular Weight 133.19
Synonym(s) Parnate
SMILES N[C@H]1[C@H](C2=CC=CC=C2)C1

Computational Chemistry Data

TPSA 26.02
LogP 1.5012
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Fatty ring compounds Cyclopropane compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(1R,2S)-2-Phenylcyclopropan-1-amine

CAS No. 3721-26-4

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