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Structure of 372120-55-3
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3-Bromo-4-(trifluoromethyl)benzaldehyde features a bromo group flanked by an electron-deficient trifluoromethyl substituent and a reactive aldehyde handle. This combination enables direct coupling in cross-coupling reactions and facilitates downstream functionalization in medicinal chemistry and materials synthesis under standard conditions.
3-Bromo-4-(trifluoromethyl)benzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its compatible bromo and aldehyde functionalities. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the aldehyde facilitates subsequent condensation or reductive amination steps. Bench-stable and readily purified by column chromatography, it functions reliably in multi-step syntheses of bioactive heterocycles and functionalized aryl scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: