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Structure of 861928-27-0
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4-Bromo-2-(trifluoromethyl)benzaldehyde features a trifluoromethyl group flanking a brominated aromatic ring, delivering enhanced electron-withdrawing character and stability. This aldehyde integrates readily into cross-coupling reactions and serves as a key intermediate in the synthesis of pharmaceuticals and functional materials.
4-Bromo-2-(trifluoromethyl)benzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling efficient Suzuki-Miyaura and Stille couplings due to its orthogonal reactivity profile. The aldehyde group facilitates direct functionalization via nucleophilic addition or condensation reactions, while the bromo and trifluoromethyl substituents offer complementary handles for cross-coupling and enhanced metabolic stability. Bench-stable and amenable to standard purification techniques, it functions reliably in multi-step syntheses of bioactive heterocycles and advanced intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: