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Structure of 37435-12-4
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7-Chloro-1H-indazole is a heterocyclic compound featuring a chlorine substituent at the 7-position of the indazole scaffold. This electron-deficient aromatic system enhances reactivity in cross-coupling processes and serves as a key pharmacophore in kinase inhibitor design. The molecule exhibits bench-stable handling characteristics and compatibility with standard synthetic protocols.
7-Chloro-1H-indazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling direct functionalization at the 3-position via palladium-catalyzed cross-coupling. Its electron-withdrawing chlorine substituent enhances metabolic stability and modulates basicity, while the indazole core provides favorable π-stacking interactions in target binding. Bench-stable and compatible with standard purification methods, it functions reliably in multistep synthesis of kinase inhibitors and CNS-active compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: