tert-Butyl (2S,4R)-4-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate

Name: tert-Butyl (2S,4R)-4-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 61478-26-0
Cat. No. CS-0021945
Purity≥97%
MDL No.MFCD02094386

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (2S,4R)-4-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate|CS-0021945

Structure of 61478-26-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

tert-Butyl (2S,4R)-4-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate features a stereochemically defined pyrrolidine core with orthogonal hydroxyl and hydroxymethyl groups. This bench-stable derivative enables direct incorporation into complex molecular architectures, serving as a key chiral building block for bioactive molecule synthesis.

Application

tert-Butyl (2S,4R)-4-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate serves as a stereochemically defined pyrrolidine building block for the synthesis of bioactive molecules. Its orthogonal functionality enables selective transformations at both the hydroxyl and hydroxymethyl groups, facilitating efficient access to complex heterocyclic scaffolds. The tert-butyl carbamate group provides stability and ease of removal under mild acidic conditions, supporting scalable synthesis and purification in medicinal chemistry workflows.

General Information

CAS No. 61478-26-0
Cat. No. CS-0021945
Purity ≥97%
MDL No. MFCD02094386
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₉NO₄
Molecular Weight 217.26
Synonym(s) None
SMILES OC[C@H]1N(C(OC(C)(C)C)=O)C[C@H](O)C1

Computational Chemistry Data

TPSA 70
LogP 0.349
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Proline and derivatives

Catalysts and Ligands Organocatalytic Small Molecules Other Catalytic Small Molecules

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Catalysis Asymmetric Synthesis Chiral Catalysts, Chiral Ligands, Chiral Reagents Chiral Organocatalysts (Other)

Catalysis Organocatalysts Asymmetric Organocatalysts

Catalysis Oxidation Oxidation Organocatalysts

Key Words

61478-26-0 sigma61478-26-0 manufacturer61478-26-0 price61478-26-0 structure61478-26-0 SDSbuy 61478-26-061478-26-0 supplier61478-26-0 uses61478-26-0 molecular weightprice of 61478-26-061478-26-0 chemical name formula of 61478-26-0

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl (2S,4R)-4-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate

CAS No. 61478-26-0

Recommended Products