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Structure of 375368-85-7
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6-Fluoro-2-methylnicotinonitrile features a fluorinated pyridine core with a nitrile group at C-3 and a methyl substituent at C-2, offering enhanced electron-withdrawing character and improved metabolic stability. This configuration enables efficient incorporation into pharmaceutical scaffolds requiring tailored lipophilicity and directed reactivity.
6-Fluoro-2-methylnicotinonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated heterocyclic scaffolds. Its nitrile and fluoro substituents provide orthogonal reactivity for downstream transformations, including hydrolysis, nucleophilic addition, and metal-catalyzed coupling reactions. The molecule exhibits good bench stability and facilitates the construction of complex pyridine-based architectures relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: