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Structure of 39959-51-8
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(2-Iodophenyl)methanamine is a bench-stable arylalkyl amine featuring an iodinated benzene ring positioned ortho to the methylene-amino group. This configuration enables direct functionalization in cross-coupling reactions, facilitating rapid access to substituted biaryl scaffolds. The iodide serves as a high-efficiency coupling handle under palladium catalysis, while the primary amine offers a versatile anchor for further derivatization.
(2-Iodophenyl)methanamine serves as a versatile building block for the synthesis of biologically relevant heterocycles and pharmaceutical intermediates. Its iodine substituent enables efficient palladium-catalyzed cross-coupling reactions, while the primary amine functionality facilitates derivatization via amidation, alkylation, or reductive amination. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: