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Structure of 375792-98-6
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1-(Bromomethyl)-4-iodo-2-nitrobenzene features a bromomethyl group flanked by iodine and a nitro substituent, enabling selective cross-coupling and functionalization. The electron-deficient aromatic core enhances reactivity in palladium-catalyzed transformations, while the bench-stable structure simplifies handling in synthetic workflows.
1-(Bromomethyl)-4-iodo-2-nitrobenzene serves as a versatile di-functional building block in cross-coupling and nucleophilic substitution workflows. The bromomethyl group enables palladium-catalyzed coupling reactions, while the iodo substituent offers orthogonal reactivity for further functionalization. The nitro group enhances electrophilicity at the aromatic ring and provides compatibility with standard reduction and cyclization protocols. This compound exhibits bench stability and facilitates efficient purification, making it well-suited for iterative synthesis of complex heterocycles and pharmaceutical intermediates.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: