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Structure of 67938-76-5
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(5-Chloropyridin-2-yl)methanamine features a pyridine ring bearing a chloro substituent at the 5-position and a primary amine group at the 2-position, enabling direct functionalization in synthetic pathways. The electron-deficient heterocycle enhances reactivity in nucleophilic substitution processes. This bench-stable, moisture-tolerant amine serves as a key scaffold for medicinal chemistry and ligand design.
(5-Chloropyridin-2-yl)methanamine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based scaffolds. Its ortho-chloro functionality permits palladium-catalyzed cross-coupling reactions, while the primary amine group facilitates conjugation via acylation, reductive amination, or salt formation. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS06,GHS05
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Signal Word : Danger
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H301-H318
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Precautionary Statements : P264-P270-P280-P301+P310-P305+P351+P338-P310-P330-P405-P501
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Lot numbers can be found on the outside label of a product: