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Structure of 376355-58-7
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This chiral phosphine ligand features a rigid dibenzodioxaphosphepin scaffold with two (S)-1-phenylethyl groups, delivering enhanced steric bulk and electronic tuning. The amine-functionalized core enables robust coordination to transition metals, facilitating efficient catalysis in asymmetric synthesis under standard conditions.
N,N-Bis((S)-1-phenylethyl)dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine serves as a chiral, bench-stable phosphine ligand that enables stereoselective cross-coupling reactions. Its rigid dioxaphosphepin core provides strong electron-donating character and enhanced steric control, facilitating efficient palladium-catalyzed transformations. The (S)-1-phenylethyl groups confer high enantioselectivity in asymmetric synthesis, while the ligand exhibits excellent functional group tolerance and ease of purification—ideal for medicinal chemistry and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: