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Structure of 37663-44-8
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This spirocyclic heterocycle features a rigid 3H-spiro[isobenzofuran-1,4'-piperidine] core with a protonated piperidine nitrogen, delivering enhanced metabolic stability and improved membrane permeability. The hydrochloride salt form ensures high solubility and crystalline purity, enabling reliable use in medicinal chemistry campaigns and target validation studies.
3H-Spiro[isobenzofuran-1,4'-piperidine] hydrochloride serves as a valuable spirocyclic scaffold for medicinal chemistry campaigns, offering a rigid, three-dimensional core with defined stereochemistry. Its structure combines an isobenzofuran moiety with a piperidine nitrogen, enabling diverse functionalization and enhancing metabolic stability. The hydrochloride salt improves solubility and handling, facilitating downstream coupling reactions and parallel synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: