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CS-W001157 4
Total: USD 88.00

4-Aminocinnoline-3-carboxamide

  • CAS No. 38024-35-0

  • Cat. No. CS-0664199
  • Purity≥98%
  • MDL No.MFCD03056454
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Aminocinnoline-3-carboxamide|CS-0664199

Structure of 38024-35-0

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Description

4-Aminocinnoline-3-carboxamide features a fused heterocyclic core with strategically positioned amino and carboxamide groups, enabling direct integration into kinase inhibitor scaffolds. This electron-rich framework supports hydrogen bonding and π-stacking interactions in target binding pockets, enhancing affinity and selectivity in medicinal chemistry applications.

Application

4-Aminocinnoline-3-carboxamide serves as a versatile heterocyclic building block for medicinal chemistry and catalytic process development. Its dual amine and carboxamide functionalities enable diverse coupling reactions, including amide bond formation and transition-metal-catalyzed cross-couplings. The scaffold exhibits good bench stability and facilitates purification via standard chromatographic methods, supporting its use in iterative synthesis of kinase inhibitors and other bioactive molecules.

General Information

  • CAS No. 38024-35-0
  • Cat. No. CS-0664199
  • Purity ≥98%
  • MDL No. MFCD03056454
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₄O
  • Molecular Weight 188.19
  • Synonym(s) None
  • SMILES C1=CC=C2C(=C1)C(=C(N=N2)C(=O)N)N

Computational Chemistry Data

  • TPSA   94.89
  • LogP   0.3109
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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