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Structure of 38076-76-5
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6-Chloro-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid features a chlorinated pyridone core that enhances electronic withdrawal and metabolic stability. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and antimicrobial agents, offering improved solubility and predictable reactivity under standard conditions.
6-Chloro-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid serves as a versatile building block for pyridine-based heterocycles, enabling efficient access to medicinally relevant scaffolds. Its chlorine substituent facilitates nucleophilic aromatic substitution and palladium-catalyzed coupling reactions, while the carboxylic acid group supports direct derivatization or activation for amide bond formation. The compound exhibits good bench stability and compatibility with standard synthetic workflows, making it suitable for iterative synthesis in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: