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Structure of 38186-85-5
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2-Bromo-5-fluoro-3-methylpyridine features a trifunctional pyridine core enabling seamless integration into diverse synthetic pathways. The ortho-bromo and para-fluoro substituents facilitate cross-coupling reactions, while the methyl group enhances regioselectivity. This bench-stable, moisture-tolerant heterocycle serves as a key building block for pharmaceutical intermediates and functional materials.
2-Bromo-5-fluoro-3-methylpyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the fluorine and methyl substituents offer orthogonal functionalization potential. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for modular heterocycle synthesis and API development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: