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Structure of 383128-41-4
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2-(2-Fluorophenyl)piperidine is a fluorinated piperidine derivative featuring a 2-fluorophenyl group attached to the nitrogen atom. This structural motif imparts enhanced metabolic stability and improved membrane permeability, making it a valuable scaffold in medicinal chemistry for CNS-targeted drug discovery. The electron-withdrawing fluorine substituent modulates electronic distribution across the aromatic ring, influencing binding affinity and selectivity in target proteins.
2-(2-Fluorophenyl)piperidine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard coupling and functionalization reactions. Its fluorinated aryl group enhances metabolic stability and modulates pharmacokinetic properties. The piperidine core offers a basic nitrogen for salt formation and conjugation, while the molecule exhibits good bench stability and compatibility with common synthetic protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: