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CS-W001157 4
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2-(Benzyloxy)-1-ethanamine

  • CAS No. 38336-04-8

  • Cat. No. CS-W018620
  • Purity≥96%
  • MDL No.MFCD00235180

*For research and further manufacturing use only, not for direct human use.

2-(Benzyloxy)-1-ethanamine|CS-W018620

Structure of 38336-04-8

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General Information

  • CAS No. 38336-04-8
  • Cat. No. CS-W018620
  • Purity ≥96%
  • MDL No. MFCD00235180
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO
  • Molecular Weight None
  • Synonym(s) 2-(Benzyloxy)ethylamine
  • SMILES NCCOCC1=CC=CC=C1

Description

2-(Benzyloxy)-1-ethanamine features a benzyl ether-linked amine functionality, offering enhanced stability and solubility in polar solvents. This bifunctional scaffold integrates a nucleophilic amine with a protected hydroxyl group, enabling selective derivatization in synthetic sequences. The compound serves as a valuable intermediate for bioconjugation and medicinal chemistry applications.

Application

2-(Benzyloxy)-1-ethanamine serves as a versatile bifunctional building block, enabling efficient synthesis of amino-alcohol scaffolds and β-amino ether derivatives. Its benzyloxy group provides orthogonal protection for hydroxyl functionalities, while the primary amine facilitates coupling reactions, nucleophilic substitutions, and incorporation into peptidomimetics or bioactive heterocycles. The compound exhibits good bench stability and ease of purification, making it suitable for iterative synthetic sequences in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3267
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.1619
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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