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Structure of 38427-94-0
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tert-Butyl pyridin-2-ylcarbamate features a pyridin-2-ylcarbamate moiety with a bulky tert-butyl protecting group, enabling stable storage and convenient deprotection under mild acidic conditions. This combination enhances handling and integration into multi-step synthesis workflows.
tert-Butyl pyridin-2-ylcarbamate serves as a robust protecting group for primary amines in pyridine-based scaffolds, enabling selective functionalization at the 2-position. Its stability under diverse reaction conditions facilitates sequential transformations in medicinal chemistry workflows. The carbamate moiety readily cleaves under mild acidic conditions, allowing access to the free amine without epimerization or side reactions. This property makes it particularly valuable in the synthesis of heterocyclic intermediates and API precursors requiring orthogonal protection strategies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H317
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Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: