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Structure of 38557-71-0
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2-Chloro-6-methylpyrazine is a heterocyclic compound featuring a pyrazine core substituted with chlorine at C2 and a methyl group at C6. This configuration imparts enhanced electron deficiency and improved stability under standard handling conditions, enabling its use in synthetic routes requiring robust, moisture-tolerant building blocks.
2-Chloro-6-methylpyrazine serves as a versatile heterocyclic building block in medicinal chemistry and agrochemical synthesis. Its electrophilic chlorine at C2 enables palladium-catalyzed cross-coupling reactions, while the methyl group at C6 offers a handle for further functionalization. The pyrazine core provides metabolic stability and favorable pharmacophore properties, facilitating integration into bioactive scaffolds. Bench-stable and readily purified by flash chromatography, it functions effectively in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: