4-Bromo-2-chlorophenylamine

Name: 4-Bromo-2-chlorophenylamine
Brand: ChemScene
Availability: InStock
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CAS No. 38762-41-3
Cat. No. CS-W020030
Purity≥97%
MDL No.MFCD00007660

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 38762-41-3

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Description

4-Bromo-2-chlorophenylamine features a dual halogenated aromatic core enabling direct functionalization in cross-coupling and electrophilic substitution reactions. The ortho-chloro and para-bromo substituents deliver enhanced reactivity while maintaining stability under standard conditions, facilitating efficient access to complex heterocyclic scaffolds and pharmaceutical intermediates.

Application

4-Bromo-2-chlorophenylamine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of bromo- and chloro-substituted aryl amine motifs. Its stability under standard reaction conditions facilitates palladium-catalyzed cross-coupling, Buchwald–Hartwig amination, and electrophilic substitution reactions. The ortho-halogenated scaffold supports sequential functionalization and offers predictable regioselectivity, making it ideal for constructing complex heterocyclic systems and API intermediates.

General Information

CAS No. 38762-41-3
Cat. No. CS-W020030
Purity ≥97%
MDL No. MFCD00007660
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₅BrClN
Molecular Weight 206.47
Synonym(s) Aniline, 4-bromo-2-chloro-
SMILES NC1=CC=C(Br)C=C1Cl

Computational Chemistry Data

TPSA 26.02
LogP 2.6847
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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4-Bromo-2-chlorophenylamine

CAS No. 38762-41-3

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