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Structure of 3885-29-8
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Methyl 5-oxotetrahydrofuran-2-carboxylate features a reactive α,β-unsaturated carbonyl system within a saturated heterocyclic framework, enabling efficient conjugate additions and cycloadditions. The ester functionality enhances solubility in polar organic solvents while maintaining stability under standard bench conditions. This scaffold serves as a key building block in the synthesis of bioactive heterocycles and natural product analogs.
Methyl 5-oxotetrahydrofuran-2-carboxylate serves as a versatile synthon in heterocyclic synthesis, enabling efficient access to oxygenated carbocyclic and heterocyclic scaffolds. Its α,β-unsaturated γ-lactone functionality facilitates nucleophilic addition and cycloaddition reactions, while the ester group supports subsequent transformations such as reduction or hydrolysis. Bench-stable and readily purified by distillation or chromatography, it functions effectively in multi-step sequences requiring functional group compatibility and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: