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Structure of 4344-84-7
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5-Oxotetrahydrofuran-2-carboxylic acid features a cyclic β-keto acid scaffold with enhanced stability and reactivity. This structure integrates a carbonyl group at the 5-position and a carboxylic acid at C2, enabling efficient functionalization in synthetic sequences. The molecule serves as a valuable intermediate for heterocyclic and peptidomimetic syntheses, particularly under mild conditions.
5-Oxotetrahydrofuran-2-carboxylic acid serves as a versatile building block in synthetic organic chemistry, enabling efficient access to γ-lactone and tetrahydrofuran scaffolds. Its dual functionality—carboxylic acid and ketone—facilitates selective transformations, including nucleophilic additions and condensations, under mild conditions. The compound exhibits good bench stability and compatibility with common protecting group strategies, making it suitable for iterative synthesis of complex heterocycles and natural product analogs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: