Z-Glu(OtBu)-OH

Name: Z-Glu(OtBu)-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 3886-08-6
Cat. No. CS-W008326
Purity≥97%
MDL No.MFCD00038274

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 3886-08-6

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Description

Z-Glu(OtBu)-OH is a protected glutamic acid derivative featuring a benzyl (Z) group at the α-amino position and a tert-butyl ester at the side-chain carboxylate. This configuration enables stable incorporation into peptide synthesis workflows, offering selective protection for both amine and carboxylic acid functionalities under standard coupling conditions.

Application

Z-Glu(OtBu)-OH serves as a key chiral building block in peptide synthesis, offering stable protection of both the α-amino and side-chain carboxyl groups. The benzyloxycarbonyl (Z) group enables efficient N-terminal protection, while the tert-butyl ester facilitates selective deprotection under mild acidic conditions. Its compatibility with standard coupling reagents and robustness during multi-step sequences make it ideal for synthesizing complex peptide scaffolds and bioactive oligomers.

General Information

CAS No. 3886-08-6
Cat. No. CS-W008326
Purity ≥97%
MDL No. MFCD00038274
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₇H₂₃NO₆
Molecular Weight 337.37
Synonym(s) None
SMILES O=C([C@H](CCC(OC(C)(C)C)=O)NC(OCC1=CC=CC=C1)=O)O

Computational Chemistry Data

TPSA 101.93
LogP 2.4879
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 7

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H317-H319-H335
Precautionary Statements : P261-P264-P271-P272-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Other Classifications

Life Science Amino Acids and their Derivatives Glutamic acid and derivatives

Life Science Amino Acids and their Derivatives N-protected amino acid

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

Key Words

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Z-Glu(OtBu)-OH

CAS No. 3886-08-6

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