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CS-W001157 4
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L-Asparagine

  • CAS No. 70-47-3

  • Cat. No. CS-0009702
  • Molecule weight132.12
  • Purity≥98%
  • MDL No.MFCD00064401

*For research and further manufacturing use only, not for direct human use.

L-Asparagine|CS-0009702

Structure of 70-47-3

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General Information

  • CAS No. 70-47-3
  • Cat. No. CS-0009702
  • Purity ≥98%
  • MDL No. MFCD00064401
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈N₂O₃
  • Molecular Weight 132.12
  • Synonym(s) (-)-Asparagine; Asn; Asparamide
  • SMILES N[C@H](C(O)=O)CC(N)=O

Description

L-Asparagine is a polar, neutral amino acid featuring a carboxamide side chain that enhances solubility and hydrogen-bonding capacity. This structural motif supports its role in protein folding stability and serves as a key nitrogen donor in biosynthetic pathways. The molecule exhibits bench-stable behavior under standard conditions, enabling reliable use in cell culture media and peptide synthesis workflows.

Application

L-Asparagine serves as a key building block in peptide synthesis and protein engineering, offering reliable side-chain amide functionality for site-specific conjugation and structural stabilization. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient incorporation into synthetic peptides and bioconjugates. Functions as a critical residue in the construction of biologically active scaffolds and glycoprotein analogs.

Synthesis

  • Route1

    References

    • Chen, Chun-Chi; Rajagopal, Basker; Liu, Xuan Yu; Chen, Kuan Lin; Tyan, Yu-Chang; Lin, Fui; Lin, Po-Chiao Amino Acids, 2014 , vol. 46, # 2 p. 367 - 374
  • Route2

    References

    • Gani, David; Young, Douglas W.; Carr, David M.; Poyser, J. Philip; Sadler, Ian H. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 11 p. 2811 - 2814
  • Route3
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      97347-33-6
    • ~75%
    • In-stock
      L-Asparagine|CS-0009702
      70-47-3

    References

    • Yoshifuji, Shigeyuki; Tanaka, Ken-ichi; Nitta, Yoshihiro Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 7 p. 2994 - 3001

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   106.41
  • LogP   -1.7263
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   3

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