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Structure of 39205-87-3
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3-Nitro-1H-pyrazole-4-carbonitrile features a dual functional group motif—electron-deficient nitro and nitrile moieties—positioned ortho to each other on the pyrazole ring. This arrangement enhances reactivity in transition-metal-catalyzed couplings and facilitates incorporation into bioactive heterocycles. The compound exhibits bench-stable handling characteristics and high solubility in polar organic solvents, streamlining use in synthetic workflows.
3-Nitro-1H-pyrazole-4-carbonitrile serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its dual electron-withdrawing nitro and nitrile groups enable selective functionalization at C3 and C4 positions, facilitating nucleophilic substitution, metal-catalyzed coupling, and cyclization reactions. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthesis of pyrazole-based scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: