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Structure of 4595-61-3
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5-Carboxypyrimidine features a pyrimidine core functionalized with a carboxylic acid group at the 5-position, enabling direct conjugation or salt formation. This electron-deficient heterocycle integrates readily into bioactive scaffolds and serves as a key building block in medicinal chemistry, particularly for kinase inhibitors and nucleoside analogs.
5-Carboxypyrimidine serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive scaffolds via amide bond formation or decarboxylation strategies. Its pyrimidine core provides structural rigidity and hydrogen-bonding capacity, while the carboxylic acid group offers high functional group tolerance and facilitates purification through salt formation. Bench-stable and compatible with standard coupling protocols, it functions effectively in peptide-like conjugations and heterocyclic derivatization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: