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CS-W001157 4
Total: USD 88.00

5-Carboxypyrimidine

  • CAS No. 4595-61-3

  • Cat. No. CS-B0029
  • Purity≥96%
  • MDL No.MFCD00856162
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Carboxypyrimidine|CS-B0029

Structure of 4595-61-3

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Description

5-Carboxypyrimidine features a pyrimidine core functionalized with a carboxylic acid group at the 5-position, enabling direct conjugation or salt formation. This electron-deficient heterocycle integrates readily into bioactive scaffolds and serves as a key building block in medicinal chemistry, particularly for kinase inhibitors and nucleoside analogs.

Application

5-Carboxypyrimidine serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive scaffolds via amide bond formation or decarboxylation strategies. Its pyrimidine core provides structural rigidity and hydrogen-bonding capacity, while the carboxylic acid group offers high functional group tolerance and facilitates purification through salt formation. Bench-stable and compatible with standard coupling protocols, it functions effectively in peptide-like conjugations and heterocyclic derivatization workflows.

General Information

  • CAS No. 4595-61-3
  • Cat. No. CS-B0029
  • Purity ≥96%
  • MDL No. MFCD00856162
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄N₂O₂
  • Molecular Weight 124.10
  • Synonym(s) Pyrimidine-5-carboxylic acid
  • SMILES O=C(O)C1=CN=CN=C1

Computational Chemistry Data

  • TPSA   63.08
  • LogP   0.1748
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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