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CS-W001157 4
Total: USD 88.00

3-Chloro-1-(4-chlorophenyl)propan-1-one

  • CAS No. 3946-29-0

  • Cat. No. CS-W015474
  • Purity≥95%
  • MDL No.MFCD00000992

*For research and further manufacturing use only, not for direct human use.

3-Chloro-1-(4-chlorophenyl)propan-1-one|CS-W015474

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General Information

  • CAS No. 3946-29-0
  • Cat. No. CS-W015474
  • Purity ≥95%
  • MDL No. MFCD00000992
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈Cl₂O
  • Molecular Weight 203.06
  • Synonym(s) CHEMPACIFIC 42352
  • SMILES ClCCC(=O)C1=CC=C(Cl)C=C1

Description

3-Chloro-1-(4-chlorophenyl)propan-1-one features a conjugated aryl-ketone scaffold with dual chlorine substituents enhancing electron-withdrawal and metabolic stability. This bench-stable ketone integrates readily into synthetic routes for pharmaceutical intermediates, offering high reactivity in nucleophilic additions and condensation reactions under standard conditions.

Application

3-Chloro-1-(4-chlorophenyl)propan-1-one serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of pharmaceutical intermediates and functionalized heterocycles. Its dual electron-withdrawing chlorine substituents enhance electrophilicity at the carbonyl carbon, facilitating nucleophilic addition and condensation reactions. The molecule exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314-H335
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   3.1516
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

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