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Structure of 39481-22-6
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Tetrabutylammonium 2,2,2-trifluoroacetate delivers a robust trifluoromethyl anion equivalent under mild conditions. This bench-stable salt features a lipophilic counterion that enhances solubility in organic media, enabling efficient carbon–carbon bond formation. The electron-deficient trifluoromethyl group facilitates nucleophilic transfer reactions with electrophiles such as carbonyls and imines.
Tetrabutylammonium 2,2,2-trifluoroacetate serves as a stable, bench-friendly source of trifluoromethyl anion equivalents in nucleophilic trifluoromethylation reactions. Its high solubility in organic solvents and compatibility with a range of electrophiles enables efficient C–CF₃ bond formation under mild conditions. The reagent facilitates the introduction of trifluoromethyl groups into heterocycles, aryl halides, and carbonyl compounds, offering reliable functional group tolerance and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P362+P364
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Lot numbers can be found on the outside label of a product: