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Structure of 395101-67-4
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3-Bromo-1H-indazole-5-carbonitrile features a bromine substituent at the 3-position and a nitrile group at the 5-position of the indazole core, creating a bifunctional scaffold with enhanced reactivity for cross-coupling and bioconjugation. The electron-deficient aromatic system facilitates transition metal-catalyzed transformations, while the nitrile group offers synthetic versatility in amide and heterocycle formation. This compound serves as a key intermediate in medicinal chemistry and materials science applications.
3-Bromo-1H-indazole-5-carbonitrile serves as a versatile building block for the synthesis of heterocyclic scaffolds in medicinal chemistry. The molecule combines a bromo substituent for palladium-catalyzed cross-coupling reactions with a nitrile group amenable to hydrolysis or cyclization, enabling access to diverse indazole-based pharmacophores. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient downstream functionalization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: