Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-5-carboxamide

  • CAS No. 395101-84-5

  • Cat. No. CS-0452185
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-5-carboxamide|CS-0452185

Structure of 395101-84-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 395101-84-5
  • Cat. No. CS-0452185
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₄BrN₃O₂
  • Molecular Weight 324.17
  • Synonym(s) None
  • SMILES NC(C=1C=CC2=C(C1)C(Br)=NN2C3OCCCC3)=O

Description

3-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1-H-indazole-5-carboxamide is a bench-stable, moisture-tolerant heterocyclic building block featuring a brominated indazole core and a tetrahydropyran-protected amine. This combination enables direct incorporation into Suzuki-Miyaura couplings and late-stage diversification in medicinal chemistry campaigns.

Application

3-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1-H-indazole-5-carboxamide serves as a versatile building block in medicinal chemistry, enabling late-stage functionalization via palladium-catalyzed cross-coupling. The bromo group facilitates efficient C–C and C–heteroatom bond formation, while the tetrahydro-2H-pyran-2-yl protecting group ensures stability and orthogonal deprotection under mild acidic conditions. Its indazole core provides a rigid, planar scaffold with favorable pharmacophoric properties, making it well-suited for targeted synthesis of kinase inhibitors and other bioactive heterocycles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   70.14
  • LogP   2.5968
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 395101-84-5 sigma395101-84-5 manufacturer395101-84-5 price395101-84-5 structure395101-84-5 SDSbuy 395101-84-5395101-84-5 supplier395101-84-5 uses395101-84-5 molecular weightprice of 395101-84-5395101-84-5 chemical name formula of 395101-84-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label