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Structure of 396076-60-1
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Ethyl 7-bromo-5-fluoro-1H-indole-2-carboxylate is a halogenated indole derivative featuring strategic bromo and fluoro substitutions at the 7- and 5-positions, respectively. This electron-deficient scaffold integrates readily into transition-metal-catalyzed cross-coupling reactions, enabling efficient access to complex heterocyclic architectures in medicinal chemistry and materials science applications.
Ethyl 7-bromo-5-fluoro-1H-indole-2-carboxylate serves as a versatile building block for the synthesis of biologically relevant indole derivatives. Its compatibility with palladium-catalyzed cross-coupling reactions enables efficient construction of substituted indole scaffolds. The bromo and fluoro substituents provide orthogonal reactivity for sequential functionalization, while the ester group facilitates further transformations. This compound exhibits good bench stability and is readily purified by standard chromatographic methods, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: