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Structure of 39890-98-7
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2,6-Dichloro-4-(trifluoromethyl)pyridine features a pyridine core with electron-withdrawing chlorine and trifluoromethyl groups positioned for enhanced electrophilicity. This combination enables efficient coupling reactions in pharmaceutical synthesis, particularly in constructing heterocyclic scaffolds under mild conditions. The molecule exhibits good stability and solubility in common organic solvents, facilitating handling in process development workflows.
2,6-Dichloro-4-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of functionalized heterocycles. Its electron-deficient pyridine core facilitates nucleophilic substitution reactions at C2 and C6 positions, while the trifluoromethyl group enhances metabolic stability and lipophilicity. The compound exhibits good bench stability and is compatible with standard coupling protocols, simplifying purification and scale-up.
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: