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Structure of 39891-09-3
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2-Chloropyridine-5-acetonitrile features a chlorinated pyridine core paired with a nitrile-bearing acetyl side chain, enabling direct integration into heterocyclic synthesis. The electron-deficient pyridine ring facilitates nucleophilic substitution, while the acetonitrile group serves as a versatile handle for further functionalization under standard conditions.
2-Chloropyridine-5-acetonitrile serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the 3-position via palladium-catalyzed cross-coupling. The nitrile group offers high stability and compatibility with diverse reaction conditions, while the chloropyridine moiety facilitates efficient derivatization through nucleophilic substitution or transition-metal-catalyzed coupling. Its bench-stable nature and predictable reactivity make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: