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Structure of 40003-48-3
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This 2-chloro-4-methyl-1,3-thiazole-5-carboxylic acid features a chlorinated thiazole core with a methyl substituent and a carboxylic acid handle, enabling direct integration into bioactive scaffolds. The electron-deficient heterocycle pairs effectively with nucleophilic partners in coupling reactions, offering a robust platform for medicinal chemistry and materials synthesis under standard conditions.
2-Chloro-4-methyl-1,3-thiazole-5-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. Its functional group array—comprising a reactive chloro substituent, methyl group, and carboxylic acid—enables diverse transformations including nucleophilic substitution, amide formation, and coupling reactions. The molecule exhibits good bench stability and facilitates efficient purification, making it well-suited for use in multi-step syntheses of bioactive molecules and API intermediates.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: