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Structure of 74346-19-3
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4-Bromo-2,6-dimethylbenzoic acid features a bromine atom at the para position relative to the carboxylic acid group, flanked by two methyl substituents at the ortho positions. This steric and electronic profile enhances stability and directs electrophilic substitution reactions with high regioselectivity. The compound serves as a key intermediate in pharmaceutical synthesis and functional material design.
4-Bromo-2,6-dimethylbenzoic acid serves as a versatile building block in medicinal chemistry and synthetic organic chemistry. Its electron-deficient aromatic core, combined with orthogonal functional handles—bromine for cross-coupling and carboxylic acid for derivatization—enables efficient construction of complex scaffolds. The methyl groups enhance steric control and metabolic stability, while the compound exhibits excellent bench stability and ease of purification, facilitating integration into standard coupling and amide formation protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: